Types of Cannabinoids Explained
What Are Cannabinoids?
Cannabinoids are naturally occurring compounds found in the cannabis plant that interact with the human endocannabinoid system. While cannabis has been cultivated and consumed for generations, only in recent decades have scientists started mapping out the plant’s diverse chemical makeup.
These compounds, which include cannabinoids, terpenes, and flavonoids, contribute to the plant’s overall chemical fingerprint. Researchers have proposed that these elements work in synergy - a concept commonly referred to as the “entourage effect.” While ongoing research continues to explore this theory, cannabinoids remain the centerpiece of cannabis study and formulation.
Major Cannabinoids: THC, CBD, CBN
THC (Tetrahydrocannabinol)
Recognized as one of the most prevalent cannabinoids in cannabis, THC is known for becoming active when heat is applied. Whether in flower, concentrates, or other formats, its presence and proportion are key factors for product formulation.
CBD (Cannabidiol)
CBD is widely used across various product categories. Found in both hemp and cannabis, it appeals to consumers looking for cannabinoid-based options without psychoactivity. Due to its federal legal status in hemp-derived forms, CBD has become mainstream in wellness circles.
CBN (Cannabinol)
CBN is derived from THC through a natural oxidation process. As cannabis ages, CBN levels can rise, and specialized extraction methods can isolate it for infusion into various products.
Emerging and Lesser-Known Cannabinoids
THC-A (Tetrahydrocannabinolic Acid)
The raw, non-activated form of THC, THC-A converts to THC when exposed to heat. It's most commonly used in concentrate formats such as diamonds and infused flower, where vaporization activates it.
THC-V (Tetrahydrocannabivarin)
Typically found in cultivars with African landrace origins, like Durban Poison, THC-V is gaining traction in niche cannabis markets. Though it shares structural similarities with THC, it expresses distinct properties during extraction and formulation.
CBG (Cannabigerol)
CBG serves as the parent molecule to major cannabinoids like THC and CBD. This compound appears early in the plant’s lifecycle, and breeders are now cultivating strains that preserve elevated CBG levels for use in isolate and full-spectrum extracts.
CBC (Cannabichromene)
Generally present in small amounts, CBC has been studied for how it interacts with other cannabinoids. Its inclusion in tinctures and topicals is growing as full-spectrum formulations gain popularity.
Delta-8 THC
Delta-8 THC is typically synthesized from hemp-derived CBD and is structurally different from Delta-9 THC. Its popularity has grown in states without adult-use cannabis laws due to its availability in vape pens, infused flower, and other compliant products.
How Cannabinoids Are Formed
Cannabinoids originate in the cannabis plant through biosynthesis. Initially, the plant generates cannabigerolic acid (CBGA), which serves as a foundational compound. From CBGA, enzymes create other cannabinoid acids like THC-A and CBD-A. These acidic precursors must be decarboxylated - typically through heating - to become active.
This biological process explains why raw cannabis and heat-activated products offer distinctly different cannabinoid profiles. Concentrates, for instance, are often engineered to emphasize activated cannabinoids through this conversion.
Strains and Chemical Profiles
Every cannabis strain, or cultivar, features a unique chemical makeup. This includes not only cannabinoids but also terpenes and flavonoids. These elements define everything from aroma and color to how the product might be used.
For example:
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Strains with dominant limonene and pinene are often associated with citrusy or forest-like notes.
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Myrcene and caryophyllene are commonly found in cultivars that exhibit deeper, more herbal characteristics.
At STIIIZY, our cultivation methods prioritize maintaining full-spectrum integrity, ensuring that each product delivers a refined expression of the strain’s native chemical blueprint.
Choosing the Right Cannabinoid
Your choice of cannabinoid should reflect your personal preferences, intended use, and familiarity with different formats. Here's a quick guide:
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THC-A - For those who enjoy high-temperature formats like dabs or infused flower.
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THC-V - An option for enthusiasts seeking less common cannabinoids with unique chemical behavior.
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CBG - Popular among consumers interested in cannabinoid blends without intoxicating effects.
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CBC - Commonly paired with other cannabinoids for a broader chemical profile.
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Delta-8 THC - Often selected in jurisdictions without access to traditional cannabis products.
Always look for products that are clearly labeled, lab-tested, and manufactured by reputable brands to ensure quality and transparency.
The Future of Cannabis Research
With federal regulations easing and public interest growing, scientific research into cannabis is progressing faster than ever. New discoveries are being made about cannabinoid interactions, genetic variance in cannabis cultivars, and advanced extraction techniques.
The next generation of cannabis research may include:
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Genetic mapping of consumer responses to cannabinoids
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Development of minor cannabinoid profiles for specific applications
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Enhanced cultivation techniques that improve cannabinoid yields and chemical consistency
STIIIZY remains dedicated to innovation and transparency. Our team continuously monitors industry advancements to stay at the forefront of cannabis science and bring well-crafted products to market.
FAQs
Delta-8 THC is typically derived from hemp through a conversion process. While it occurs naturally in small quantities, most Delta-8 on the market is synthesized for commercial use.
Legality depends on the specific cannabinoid and jurisdiction. Always verify local laws before purchasing or consuming cannabis products.
No. While both are non-intoxicating, they are chemically distinct and play different roles in the cannabis plant’s lifecycle.
Not always. Some products are formulated to highlight specific cannabinoids. Always check the product label or lab results to confirm cannabinoid content.
STIIIZY complies with all applicable state laws regarding the sale and marketing of cannabis products. This content is intended for adults 21+ in jurisdictions where cannabis use is legal under state law. By engaging with this material, you acknowledge that you are of legal age in your jurisdiction.
This content is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease or medical condition. STIIIZY makes no health claims about cannabis products. Consult a licensed healthcare professional before using cannabis, especially if you are pregnant, nursing, or have a medical condition.
Cannabis products may affect individuals differently. Consume responsibly and avoid operating vehicles or machinery after use. STIIIZY disclaims all liability for any adverse effects, legal consequences, or misuse resulting from the use of our products or reliance on this content.
Cannabis laws vary by state and locality. This content does not constitute legal advice. Users are responsible for understanding and complying with their local regulations.
Statements about product effects or benefits are based on general industry knowledge and user experiences. Individual results may vary. STIIIZY does not guarantee specific outcomes.
References to third-party studies, testimonials, or external resources are provided for context only. STIIIZY does not endorse or validate these materials unless explicitly stated.
The views and opinions expressed in this blog are those of the author and do not necessarily reflect the official policy or position of STIIIZY.
